Sheldon Lee Glashow

... Why is the muon, some dumb particle, 200 times heavier than the electron? Why is the proton about 2,000 times heavier than the electron? Why is the electric charge of the electron what it is? Why are there six quarks in nature? Why not seven or eleven or five? There are many, many "why" questions. Also a number of 'how' questions. What is the mechanism that causes the weak interactions to be weak and the electromagnetic interactions not weak?

— Sheldon Lee Glashow

All kinds of questions remain. Many have to do with cosmology. How did the universe originate? How did the galaxies become distributed in space like the suds in the kitchen sink, as one of my colleagues has described it? Why is the cosmological constant apparently very tiny but non-zero and has a peculiar value that leads the universe to expand more rapidly?

— Sheldon Lee Glashow