Black holes set a limitation on the number of species of elementary particles—quarks, leptons, neutrinos—which may exist. And black holes lead to a fundamental limitation on the rate at which information can be transferred for given message energy by any communication system.
The DM halo hypothesis is evidently an attempt to resolve the acceleration discrepancy within orthodox gravitation theory. But in coming to terms with this discrepancy, suspicion fell on Newtonian gravity already early in the game. Zwicky, who had exposed the acceleration discrepancy in clusters of galaxies ..., opined much later that the discrepancy may reflect a failure of conventional physics ...
There is a prescription that works well, MOND, but the reason it works so well is not known. You may say that MOND tells us how the real theory of gravity should look.